Industrial Scale
Columns built to meet the demands of large-batch pharmaceutical manufacturing.
Creating precision Chromatography Columns in the USA
About Mann Welding
With decades of experience and a portfolio of groundbreaking patents, Mann Welding is the premier provider of chromatography columns. Our solutions deliver unparalleled performance in pharmaceutical and industrial separations.
With a focus on quality and compliance, we help organizations achieve consistent separation results while reducing downtime and overall cost of ownership.
Capabilities
ASME-certified, US-based fabrication
- Materials
- 316L stainless steel, C-22 Hastelloy, acrylic
- Inner diameter
- 45–180 cm (custom sizes by request)
- Bed height
- Built to your process requirements
- Hygienic finishes
- Electropolished, GMP-ready design paths
- Validation
- IQ/OQ documentation packages available
- Compliance
- USP Class VI polymeric materials (when specified)
- Origin
- Designed & fabricated in the USA
Company History
- 1955
Founded
Started as a family shop building carbon and stainless-steel storage tanks for the chemical and carpet industries, earning a reputation for tight tolerances and reliable welds.
- 1988
Entering Pharma
Began fabricating tanks for Eli Lilly, adopting GMP-ready practices, sanitary finishes, and documentation standards that set the foundation for pharmaceutical equipment work.
- 1990
First Chromatography Prototype
Built our first prototype chromatography column in 316L stainless steel with sanitary connections and precision flow distribution—designed for pilot-scale bioprocessing and easy CIP/SIP.
- 1993
First Patent Awarded
Secured our first patent for chromatography column design, improving flow uniformity and turnaround time. This milestone accelerated our shift into large-scale pharmaceutical separation systems.
Interested in getting a quote?
Let us know what your product specifications require and we can produce a custom chromatography column based on your requirements.
Patented Technology
Decades of protected innovation
From our first chromatography column patent in 1994 to later advances in hydraulic column control, Mann Welding’s designs are backed by issued U.S. patents — improving flow uniformity, packing efficiency, and turnaround for large-scale separation.
Chromatography Columns
Patented Technology
Innovations such as slurry fill methods, variable speed operation, and integrated hydraulic systems.
Engineered for Reliability
Straightforward column setup, PLC controlled leveling, and repeatable recipes.
Trusted by global pharma leaders
From the world’s largest pharmaceutical manufacturers to fast-moving biotech teams, Mann Welding is a proven partner for chromatography fabrication. Our work is trusted in critical environments where quality, repeatability, and on-time delivery matter most.
Contact Us
Contact Sales
Looking for specs, pricing, or guidance on which chromatography column is right for your application? Our sales team is here to answer questions, provide technical details, and help you get the right solution in place.
Contact Our Sales TeamContact Support
Already working with a Mann Welding column and need assistance? Our support team can help with components, maintenance, and troubleshooting so your systems stay running at peak performance.
Contact Our Support Team