Chromatography Columns

Overview

The 180mm chromatography column is perfect for processing large batches of pharmaceutical products. With its precise separation capabilities, you can achieve high levels of purity and consistency in your final product. This column is designed to handle even the most complex mixtures, ensuring that you get the results you need every time.

• Scalable from 100 mm to 450 mm inner diameter (i.d.) and bed volumes from 2 up to 121 liters. Pressure rating from 2.5 bar to 8 bar, depending on column size.
• Material Certificates Reports (BPG MCR) available for ordering.
• Installation and Operational Qualification Documentation Packages available.
• Hygienic design and operation. Microbial attachment and growth is prevented through the use of calibrated precision glass, high-grade electropolished stainless steel and an absence of dead pockets.
• Easy, efficient packing and running with the single-screw adapter.
• All polymeric materials meet the requirements for USP class VI, described in USP <88> Biological Reactivity Tests, in vivo.

Overview

A rugged, shop-floor-ready control unit for reliable column packing and unpacking. The Mechanical HCU uses precision gauges and manual valves to deliver stable pressure and repeatable control without the need for firmware or software. It is ideal for regulated environments that prefer simple validation and hands-on operation.

Key benefits

• Intuitive manual operation with immediate tactile feedback
• Minimal training required and fast setup
• No software updates or network dependencies
• Easy qualification since the control path is fully visible and documented
• Low total cost of ownership

Standard features

• Stainless-steel hydraulic manifold with isolation and relief valves
• Dual glycerin-filled analog pressure gauges for coarse and fine monitoring
• Precision needle valve for controlled pressurization and depressurization
• Quick-connect lines for feed and return.
• Built-in mechanical over-pressure protectionCleanable drip tray and IP-rated enclosure

Performance snapshot

• Typical operating range: 0 to 3 bar line pressure
• Resolution at gauge: 0.1 bar
• Compatible column IDs: 10 to 60cm
• Media: approved hydraulic fluids for cleanroom use

Overview

A PLC-driven control unit for precise, recipe-based column operations. The Digital HCU offers closed-loop pressure control. Operators select a method, press start, and monitor progress on the touchscreen.

Key benefits

• Closed-loop control for stable pressure and ramp profiles
• Method recipes with step timing and setpoints for repeatability
• On-screen trends with alarms and event history

Standard features

• 7–10 inch touchscreen HMI with guided workflows
• Industrial PLC with PID pressure control
• Digital pressure transducer with high-resolution sampling
• Configurable pressure ramps, holds, and relief sequences
• User roles with password control and audit trailElectronic interlocks for over-pressure and emergency stop
• User roles with password control and audit trail
• Electronic interlocks for over-pressure and emergency stop

Performance snapshot

• Typical operating range: 0 to 3 bar line pressure
• Control resolution: ≤ 0.01 bar at the transducer
• Programmable ramps and dwell steps with second-level timing
• Compatible column IDs: 45cm to 180cm
• Media: approved hydraulic fluids for cleanroom use