Mann Welding designs and manufactures fully customizable chromatography columns built to match your process, facility constraints, and validation requirements. From pilot to production scale, we engineer columns around your target bed height, inner diameter, pressure profile, media, and cleaning approach so you can pack, run, and turn equipment faster with repeatable performance.
Columns can be built in 316L stainless steel, C-22 Hastelloy, or acrylic, depending on chemical compatibility, cleanliness standards, visibility needs, and cost targets. We also support IQ/OQ documentation packages and hygienic design practices suitable for regulated manufacturing environments.
Every Mann Welding column is engineered as a made-to-fit system. Choose the material, set your inner diameter and bed height, and specify the process details that matter most (packing method, pressure limits, cleaning strategy, sanitary interfaces, and documentation). The result is a column that integrates cleanly into your facility and supports consistent, repeatable separations at scale.
Let us know what your product specifications require and we can produce a custom chromatography column based on your requirements.
Ideal Implementation: Pilot plants, small to mid-scale GMP lines, facilities that value simplicity and manual oversight.
A rugged, shop-floor-ready control unit for reliable column packing and unpacking. The Mechanical HCU uses precision gauges and manual valves to deliver stable pressure and repeatable control without the need for firmware or software. It is ideal for regulated environments that prefer simple validation and hands-on operation.
Ideal Implementation: GMP manufacturing where repeatability, electronic records, and integration with plant systems are priorities.
A PLC-driven control unit for precise, recipe-based column operations. The Digital HCU offers closed-loop pressure control. Operators select a method, press start, and monitor progress on the touchscreen.
Columns built to meet the demands of large-batch pharmaceutical manufacturing.
Innovations such as slurry fill methods, variable speed operation, and integrated hydraulic systems.
Innovations such as slurry fill methods, variable speed operation, and integrated hydraulic systems.
Mann Welding has been applying its welding and fabrication expertise to chromatography solutions for decades. Our patented technologies and focus on process efficiency have earned us trust across pharmaceutical and biotech industries.
